Leader’s teams

The leader and originator of the FixNet project and the leader of team searching for new genetic defects in congenital neutropenia. Since 2007, professor and the head of Pediatrics, Oncology and Hematology Clinic at the Medical University of Lodz.

He is graduated from the Faculty of Biology and Earth Sciences of the University of Lodz and the Faculty of Medicine of the Medical University of Lodz. In the years 2002–2004 he did a postdoctoral fellowship at the Department of Genetics and Epidemiology, Joslin Diabetes Center, Harvard Medical School in Boston. In the years 2004–2008 he did scientific internships in the USA as a visiting researcher, affiliated by Harvard Medical School. He is a member of many scientific societies in Poland as well as abroad. He is a board member and treasurer of the Polish Society of Pediatric Oncology and Hematology, a member of the Council of the National Program for the Management of Haemophilia and Related Bleeding Disorders and the Rare Diseases Team of the Ministry of Health.

He is the author or co-author of over 290 scientific publications in journals such as “New England Journal of Medicine", “Nature Communication", “Nature Clinical Practice Neurology", “Blood, Leukemia", “Haematologica", “Diabetes", “Diabetes Care", “Diabetologia" and “Clinical Cancer Research".

Chief specialist in cell engineering, PostDoc in the project Fix Neutropenia (FIXNET): focusing on neutrophil proteases defects which serve as novel diagnostic and therapeutic options.
A biologist by profession (5-year MA studies at the Department of Biology and Environmental Protection of the University of Lodz), in 2017 she defended her doctoral thesis at the Medical Department of the Medical University of Lodz about the analysis of the IKZF1 gene variability in diffuse large B cell lymphomas. Co-author of several scientific papers, coordinator of a nationwide project dealing with the identification of the molecular basis of acute lymphoblastic leukemia in children.

For 9 years now she has been involved in works related to the analysis of genetic disorders in pediatric cancers and other childhood diseases. In the project she deals with the identification of genetic mutations in patients diagnosed with neutropenia, using new generation sequencing and direct sequencing.

She graduated Medical Biotechnology at the Medical University of Lodz. Already during her studies she completed training in the field of Clinical Research Monitoring and project management (Prince 2 Foundation). She gained experience as a implementer of research and development projects, working as a Junior R&D Specialist in a group dealing with the selection of aptamers – small molecules with therapeutic potential. Currently, as a PhD student at the Department of Immunopathology and Genetics, she carries out research work in the FixNet project regarding the molecular basis of congenital neutropenia. Privately she is smiling optimist.

Lecturer at the Department of Paediatrics, Oncology and Hematology at the Medical University of Lodz. In the FixNet project she is the leader of team developing repairing procedure for mutations identified in patients with congenital neutropenia. In May 2019, she graduated with a PhD in medical sciences at the Medical Faculty of the Medical University of Lodz, the thesis on a genetic marker for the risk stratification of therapy failure in children with acute lymphoblastic leukemia. In 2018 -2019 she did scientific internships at the DKFZ Institute (Deutsches Krebsforschungszentrum) in the Leukemogenesis Mechanisms team in Heidelberg, where she used the CRISPR technique for epigenetic regulation. She graduated the School of Molecular Medicine (SMM) at the Medical University of Warsaw, postgraduate studies of statistics in biomedical research and masters studies in Medical Biotechnology at the Medical University of Lodz.

Graduated from University of Lodz, NanoBioMedical Centre Adam Mickiewicz University of Poznan and University of Eastern Finland. He defended with distinction his doctoral dissertation last year at University of Lodz, Faculty of Biology and Environmental Protection. Since the beginning of his scientific work he has been associated with molecular biology of cancer as well as been interested in implementing knowledge and research results to clinical practice. Having opportunity to participate in many grants financed both by European Union and National Science Centre, attending international conferences and continuous improvement of qualification led him to gain over ten years of laboratory experience. As an experimenter he is reliable, responsible and inquiring, always wanting to explain the problem to the very end. Privately, he is a life and soul of the party, the person with many passions and a good sense of humor. Currently, he is employed at Department of Pediatrics, Oncology, Hematology at the Medical University of Lodz pursuing his postdoc as a chief specialist in cell engineering. Dr Krzyżanowski is being involved in an attempt to develop innovative cell therapy to treat congenital immunodeficiency within the FIXNET project.

He received his MSc in Medical Biotechnology from the University of Lodz. In 2016-2017 he completed an intership of Institute of Medical Biology, Polish Academy of Science. Currently, he is at the 4th year of doctoral studies. In his research, he focuses on understanding the mechanisms of signal transduction modulation of hematoid cells by serine-threonine kinase inhibitors. In the FixNet project, he is working on the differentiation of cell lines, that will be used to construct a cell model with selected mutations responsible for the development of severe congenital neutropenia.

A graduate of molecular medicine at the Medical University of Göttingen. She has taken internships at universities such as the Medical University of Warsaw, Harvard Medical School, and The Manipal Institute of Technology. In 2019, she returned to her hometown of Lodz and began doctoral studies at the Medical University at the Department of Paediatrics, Oncology and Hematology, where under the supervision of Joanna Madzio, PhD and Prof Wojciech Młynarski will pursue a PhD project focused on genetic editing of cells from patients with congenital neutropenia using the CRISPR / Cas9 method.